Ellis Ambrose was the son of James Ambrose and Mary Lyon.

Ellis was born around 1750.

He was christened at Rainford, Lancashire on 2nd November 1750.

Ellis married Ann Melling on Wednesday 30 October 1776 in Wigan, Lancashire.

He had the following children from his marriage to Ann Melling:

- Mary Ambrose	born around 1777.
- James Ambrose	born around 1778.
- Ellen Ambrose	born around 1780.
- Ellis Ambrose	born around 1782.
- Charlotte Ambrose	born around 1786.
- Ann Ambrose	born around 1789.
- John Ambrose	born around 1792.
- William Ambrose	born around 1794.
- Charlotte Ambrose	born around 1801 at Upholland, Lancashire.
- Mary Ambrose	born around 1802.

Details of Ellis's occupation are not known.

Details of Ellis's death are not known.