William Nicholson was born around 1752.

He was christened on Saturday 7 October 1752 at Billinge, Lancashire.

William married Hannah Ambrose on Tuesday 14 July 1778 in Wigan, Lancashire.

He had the following children from his marriage to Hannah Ambrose:

- Mary Nicholson	born around 1778.
- Betty Nicholson	born around 1780.
- John Nicholson	born around 1782.
- Ann Nicholson	born around 1783.
- William Nicholson	born around 1785 at Winstanley, Lancashire.
- Hannah Nicholson	born around 1787.
- Peter Nicholson	born around 1790.
- James Nicholson	born around 1792.
- John Nicholson	born around 1794.
- Thomas Nicholson	born around 1796 in Winstanley, Wigan, Lancashire.

Details of William's occupation are not known.

William died when he was 64 years old, on Sunday 5 January 1817 in Winstanley, Wigan, Lancashire.