Details of William's birth are not known.

William married Elizabeth Sharrad on Sunday 26 March 1741 in St Bartholomew's Church, Wednesbury, Staffordshire.

He had the following children from his marriage to Elizabeth Sharrad:

- Samuel Spittle	born around 1741.
- Isaac Spittle	born around 1743.
- David Spittle	born around 1744.
- Jane Spittle	born around 1746.
- Priscilla Spittle	born around 1747.
- Mary Spittle
- Peter Spittle	born around 1752.
- Ambrose Spittle	born around 1754.
- Mary Spittle	born around 1755.
- Fanny Spittle	born around 1757.
- Nicholas Spittle	born around 1759.
- Ruth Spittle	born around 1759.

Details of William's occupation are not known.