Isaac Spittle was the son of William Spittle and Elizabeth Sharrad.

Isaac was born around 1743.

He was christened on Thursday 25 April 1743 at St Bartholomew's Church, Wednesbury, Staffordshire.

Isaac married Martha Baker on Monday 5 November 1764 in St Bartholomew's Church, Wednesbury, Staffordshire.

He had the following children from his marriage to Martha Baker:

- William Spittle	born around 1767.
- Sarah Spittle	born around 1770.
- Phoebe Spittle	born around 1770.
- Thomas Spittle	born around 1774.
- Jenny Spittle	born around 1777.
- Jane Spittle	born around 1780.
- Mary Ann Spittle	born around 1782.
- Catherine Spittle	born around 1787.

Details of Isaac's occupation are not known.

Details of Isaac's death are not known.