Details of Betty's birth are not known.

Betty married Ellis Ambrose on Monday 6 June 1803 in Wigan, Lancashire.

She had the following children from her marriage to Ellis Ambrose:

- Jane Ambrose	born around 1808 at Winstanley, Lancashire.
- Ann Ambrose	born around 1810.
- Ellis Ambrose	born around 1812 in Shevington, Lancashire.
- James Ambrose	born around 1814.
- William Ambrose	born around 1816.
- Sibil Ambrose	born around 1818.
- Peter Ambrose	born around 1821 in Shevington, Lancashire.